Coronavirus: Corona vaccine reduces effect on these people, claims in research

Coronavirus Research: The effect of the Kovid-19 vaccine has been found to be less in people affected by high levels of air pollution before the corona virus epidemic. This has been claimed in a research.  Specifically, people exposed to fine particulate matter (PM2.5), nitrogen dioxide (NO2) and black carbon showed a 10 per cent drop in IgM and IgG antibody response prior to infection, the researchers said.

Environmental Health Perspective’ Research findings published in the journal Nature provide further evidence about the adverse effects of air pollution on the immune system.  ‘Barcelona Institute for Global Health’ (ISGlobal) Manolis Kogevinas said air pollution has adverse health effects, including lung cancer, heart and respiratory diseases and diabetes. Kogevinas said, “ Effects of air pollutants on the immune system have been observed. So in this study we wanted to determine whether air pollution also affects the antibody response to anti-COVID-19 vaccines.”

Which age group people were researched? 
The team analyzed the data of 927 participants aged 40 to 65 years. These participants answered a questionnaire and gave blood samples in the summer of 2020 and spring of 2021. All had received one or two doses of the Covid-19  vaccines AstraZeneca, Pfizer or Moderna to be administered in Spain. 

What did the research team say?
The research team assessed IgM, IgG and IgA antibodies in these people. Exposure to PM2.5, black carbon, NO2 and ozone (O3) was estimated according to the places where the participants lived before the pandemic.  The results show that the person who In those not infected with the coronavirus, exposure to PM2.5, NO2 and black carbon before the pandemic reduced vaccine-derived antibodies by 5 to 10 percent. 

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